Tahmine Tavakoli; Peyman Adibi; Mohammad Hossein Sanei; Kiyan Heshmat-Ghahdarijani
Volume 19, Issue 10 , October 2017, , Pages 1-3
Abstract
Introduction: Mucormycosis of the gastrointestinal tract is a rare invasive fungal infection and due to late diagnosis, it is associated with a high mortality rate.Case Presentation: The studied patient was a 20-year-old woman, known case of Ulcerative colitis, admitted to emergency unit of Alzahra hospital ...
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Introduction: Mucormycosis of the gastrointestinal tract is a rare invasive fungal infection and due to late diagnosis, it is associated with a high mortality rate.Case Presentation: The studied patient was a 20-year-old woman, known case of Ulcerative colitis, admitted to emergency unit of Alzahra hospital of Isfahan University Of Medical Sciences, Iran, in May of 2013 by abdominal pain, fever, and leucopenia. With possible diagnosis of typhlitis, she underwent laparotomy. Gangrene, inflammation, and obstruction of 30 centimeter of jejunum and momentum were detected. Pathology reported neutropenic enteritis due to zygomatic infection consist with intestinal mucormycosis.Conclusions: In patients with high clinical suspicion of gastrointestinal tract mucormycosis, the emergence of early diagnosis, correction of underlying risk factors, and treatment are of great importance.
Mahmoud Babaeian; Mohsen Naseri; Mohammad Kamalinejad; Farzaneh Ghaffari; Fatemeh Emadi; Awat Feizi; Rahmatollah Rafiei; Mohammad Mazaheri; Seyed Abbas Hasheminejad; Jae-Woo Park; Peyman Adibi
Volume 19, Issue 2 , February 2017, , Pages 1-10
Abstract
Background: Functional dyspepsia (FD) is a common gastrointestinal disease that has various treatments, including medicinal plants.Objectives: The current study aimed to investigate the effect of Mentha longifolia on relieving the symptoms and improving the quality of life (QOL) in patients with functional ...
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Background: Functional dyspepsia (FD) is a common gastrointestinal disease that has various treatments, including medicinal plants.Objectives: The current study aimed to investigate the effect of Mentha longifolia on relieving the symptoms and improving the quality of life (QOL) in patients with functional dyspepsia from the subgroup of postprandial distress syndrome (PDS). Patients and Methods: This randomized, double-blind, placebo-controlled trial was conducted in a gastroenterology clinic affiliated with Isfahan University of Medical Sciences. One hundred patients diagnosed with PDS according to the ROME III criteria were assigned to two groups: the M. longifolia capsules (three times daily for four weeks) group and the placebo group. Tools for gathering data were the FD severity scale and QOL (Persian version of the SF-36 questionnaire). Assessments of FD symptoms were obtained at baseline and also at the end of weeks 2, 4, and 12. QOL was evaluated at baseline and at the end of week 12.Results: At the end of treatment period, the M. longifolia group reported a more significant improvement in the mean severity scales of FD symptoms than the placebo group (P < 0.001). A significant difference was also observed between FD symptoms and severity scores in the two groups eight weeks after the medication was stopped. At the end of the fourth week, the greatest degrees of relief regarding epigastric bloating (70.5% vs. 21.4%, P < 0.001), epigastric fullness (68.2% vs. 31%, P < 0.001), loss of appetite (34.1% vs. 9.5%, P = 0.014) and early satiety (36.3% vs. 21.4%, P = 0.02) were observed in the control group. With M. longifolia, significant improvement in the scores of QOL was observed for the dimensions of general health, role-physical, social functioning, bodily pain, vitality, and mental health.Conclusions: This study showed the efficacy of M. longifolia in relieving PDS symptoms and improving the QOL of patients with PDS.
